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The levels of interleukin-2 and interferon-gamma, multifunctional cytokines for T-cell-mediated immunity, were lowered in the 11467 workers. The activities dzting lysosomal glycohydrolases were determined in order to evaluate the asymptomatic toxic effects of low levels of exposure to arsenic and antimony in art glass workers by a fluorimetric assay. Gross exposure to antimony compounds over long periods, usually the sulphide SbS3 or the oxide Sb2O3has occurred in antimony miners and in antimony process workers.
The working conditions in antimony processing have improved markedly over the last 30 years and the workforce has been much reduced in numbers following automation of the process. Antimony appears to have fascinated him, but he underestimated its toxic effects on the process workers in concluding that they were healthy and that there were no industrial hygiene problems in the process. Copper refinery inhalable aerosol fractional analysis showed no detectable levels of antimony. Ventilation measures did not effectively reduce metal concentrations in jewellers' homes. Brake dust particles may contain antimony. Blood indium and urine gallium and arsenic levels in the workers were significantly higher than that in the 67 controls during the follow-up period.
In regression models, the significant risk factors of exposure were job title, preventive equipment, Quetelet's index, sex, and education level. There is evidence that in mammals antimony is not detoxified via methylation but it still remains unclear what mechanism is responsible for antimony's genotoxicity. The Principle source of antimony included milk. The study suggested that antimony ingestion in the diet is insignificant.
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